Ginkgo Biloba Uses, Side Effects & Warnings (2024)

Generic name: ginkgo [GINK-goe]
Drug class: Herbal products

Medically reviewed by Drugs.com on Sep 28, 2023. Written by Cerner Multum.

What is Ginkgo Biloba?

Ginkgo Biloba is a plant also known as Maidenhair tree, Ginkgo Biloba biloba, Abricot Argente Japonais, Adiantifolia, Arbre aux Ecus, Arbre du Ciel, Arbre Fossile, Bai Guo Ye, Baiguo, Extrait de Ginkgo Biloba, Fossil Tree, Graine de Ginkgo Biloba, Herba Ginkgo Biloba Biloba, Japanese Silver Apricot, Kew Tree, Noyer du Japon, Pei Go Su Ye, Salisburia Adiantifolia, Yen Xing, Yinhsing, Arbe aux Quarante Ecus, Extrait de Feuille de Ginkgo Biloba, Ginkgo Biloba Folium and other names.

Ginkgo Biloba has been used in alternative medicine as a possibly effective aid in treating anxiety, certain types of dementia, premenstrual symptoms, vertigo (dizziness), stroke, schizophrenia, or a movement disorder (tardive dyskinesia) caused by taking certain antipsychotic drugs.

Ginkgo Biloba has also been used to treat memory problems, tinnitus (ringing in the ears), high blood pressure, multiple sclerosis, heart disease, and sexual problems caused by taking antidepressants. However, research has shown that Ginkgo Biloba may not be effective in treating these conditions.

Other uses not proven with research have included altitude sickness, macular degeneration (age-related vision loss), attention deficit disorder, dyslexia, vitiligo (discolored skin), migraine, lung disease, high cholesterol, Raynaud's syndrome, Lyme disease, fibromyalgia, chronic fatigue syndrome, blood clots, seasonal allergy, leg pain caused by blood circulation problems, cough, depression, sexual dysfunction in females, asthma, autism spectrum disorder, chronic kidney disease, cocaine dependence, vision problems, hemorrhoids, intestinal parasite infection, wound healing, and certain type of cancers.

It is not certain whether Ginkgo Biloba is effective in treating any medical condition. Medicinal use of this product has not been approved by the FDA. Ginkgo Biloba should not be used in place of medication prescribed for you by your doctor.

Ginkgo Biloba is often sold as an herbal supplement. There are no regulated manufacturing standards in place for many herbal compounds and some marketed supplements have been found to be contaminated with toxic metals or other drugs. Herbal/health supplements should be purchased from a reliable source to minimize the risk of contamination.

Ginkgo Biloba may also be used for purposes not listed in this product guide.

Ginkgo Biloba side effects

Get emergency medical help if you have signs of an allergic reaction (hives, difficult breathing, swelling in your face or throat) or a severe skin reaction (fever, sore throat, burning eyes, skin pain, red or purple skin rash with blistering and peeling).

Stop using Ginkgo Biloba and call your healthcare provider at once if you have:

Common side effects of Ginkgo Biloba may include:

  • stomach pain, nausea, vomiting, dry mouth;

  • diarrhea, constipation; or

  • headache, dizziness.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Ginkgo Biloba side effects (more detail)

Warnings

Follow all directions on the product label and package. Tell each of your healthcare providers about all your medical conditions, allergies, and all medicines you use.

Before taking this medicine

Before using Ginkgo Biloba, talk to your healthcare provider. You may not be able to use this product if you have certain medical conditions.

Ask a doctor, pharmacist, or other healthcare provider if it is safe for you to use this product if you have ever had:

  • diabetes;

  • seizures or epilepsy;

  • a bleeding or blood clotting disorder;

  • an allergy to plants such as poison ivy, poison oak, poison sumac;

  • food allergies; or

  • a genetic enzyme deficiency called glucose-6-phosphate dehydrogenase (G6PD) deficiency.

Ginkgo Biloba may affect fertility in men or women. Pregnancy could be harder to achieve if either parent is using this product.

Ginkgo Biloba is considered likely unsafe to use during pregnancy. Taking Ginkgo Biloba during pregnancy could cause bleeding or premature labor.

Ginkgo Biloba is considered likely unsafe to use if you are nursing a baby. Ask a doctor before using this product.

Do not give any herbal/health supplement to a child without medical advice.

How should I take Ginkgo Biloba?

When considering the use of Ginkgo Biloba, seek the advice of your doctor. You may also consider consulting a practitioner who is trained in the use of herbal/health supplements.

If you choose to use Ginkgo Biloba, use it as directed on the package or as directed by your doctor, pharmacist, or other healthcare provider. Do not use more of this product than is recommended on the label.

Ginkgo Biloba leaf extract is thought to be likely safe when taken in recommended doses. Roasted Ginkgo Biloba seeds are possibly unsafe when taken by mouth.

Fresh Ginkgo Biloba seeds in raw form are poisonous and are considered likely unsafe to eat.

Swallow the tablet or capsule whole and do not crush, chew, open or break it.

Call your doctor if your symptoms do not improve, or if they get worse.

If you need surgery, dental work, or a medical procedure, stop taking Ginkgo Biloba at least 2 weeks ahead of time. Tell your healthcare provider if you have a planned surgery.

Store at room temperature away from moisture, heat, and light.

What happens if I miss a dose?

Skip the missed dose and take the next regularly scheduled dose.

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

What should I avoid while taking Ginkgo Biloba?

Do not use different forms of Ginkgo Biloba (pills, liquids, and others) at the same time or you could have an overdose.

Avoid using Ginkgo Biloba together with other herbal/health supplements that can also affect blood-clotting. This includes angelica (dong quai), capsicum, clove, dandelion, danshen, evening primrose, garlic, ginger, horse chestnut, Panax ginseng, poplar, red clover, saw palmetto, turmeric, and willow.

Avoid using Ginkgo Biloba together with other herbal/health supplements that can increase your risk of seizures. This includes EDTA, folic acid, GBL (gamma butyrolactone), GHB (gamma hydroxybutyrate), glutamine, hyssop oil, juniper, L-carnitine (levocarnitine), melatonin, rosemary, sage, wormwood, and others.

What other drugs will affect Ginkgo Biloba?

Do not take Ginkgo Biloba without medical advice if you are using a medication to treat any of the following conditions:

  • any type of infection (including HIV, malaria, tuberculosis, or hepatitis C);

  • anxiety, depression, or a mental illness;

  • asthma or allergies;

  • cancer;

  • erectile dysfunction;

  • heartburn or gastroesophageal reflux disease (GERD);

  • high blood pressure, high cholesterol, or a heart condition;

  • migraine headaches;

  • psoriasis, rheumatoid arthritis, or other autoimmune disorders; or

  • seizures.

Do not take Ginkgo Biloba without medical advice if you are using any of the following medications:

  • insulin or oral diabetes medicine;

  • a blood thinner--warfarin, Coumadin, Jantoven; or

  • NSAIDs (nonsteroidal anti-inflammatory drugs)--aspirin, ibuprofen (Advil, Motrin), naproxen (Aleve), celecoxib, diclofenac, indomethacin, meloxicam, and others.

This list is not complete. Other drugs may affect Ginkgo Biloba, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here.

Ginkgo Biloba drug interactions (more detail)

Popular FAQ

Ginkgo biloba may interact with over 290 drugs, and most interactions are moderately clinically significant. You should usually avoid these combinations unless approved by your healthcare provider. Some important interactions can include certain HIV medicines, seizure treatments, or anticoagulants (blood thinners) like warfarin. Continue reading

More about Ginkgo Biloba (ginkgo)

  • Check interactions
  • Compare alternatives
  • Reviews (9)
  • Side effects
  • Drug class: herbal products
  • Breastfeeding
  • En español

Professional resources

  • Ginkgo biloba product monographs

Related treatment guides

  • Herbal Supplementation

Further information

  • Consult with a licensed healthcare professional before using any herbal/health supplement. Whether you are treated by a medical doctor or a practitioner trained in the use of natural medicines/supplements, make sure all your healthcare providers know about all of your medical conditions and treatments.

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circ*mstances.

Medical Disclaimer

Copyright 1996-2024 Cerner Multum, Inc. Version: 6.01.

Ginkgo Biloba Uses, Side Effects & Warnings (2024)

FAQs

Ginkgo Biloba Uses, Side Effects & Warnings? ›

When taken by mouth: Ginkgo LEAF EXTRACT is likely safe for most people. It can cause some minor side effects such as stomach upset, headache, dizziness, and allergic skin reactions. There is also some concern that ginkgo leaf extract might increase the risk of bruising and bleeding or cause arrhythmia.

Who should avoid ginkgo? ›

If you are older, have a bleeding disorder or are pregnant, don't take ginkgo. The supplement might increase your risk of bleeding. If you're planning to have surgery, stop taking ginkgo two weeks beforehand. Ginkgo might interfere with the management of diabetes.

Is it bad to take Ginkgo Biloba everyday? ›

Ginkgo biloba is generally safe and well-tolerated at doses up to 240 mg per day. Higher doses are more likely to cause side effects and drug interactions. However, lower doses can still cause side effects, such as stomach issues or headaches.

What vitamins should not be taken with Ginkgo Biloba? ›

Avoid using ginkgo together with other herbal/health supplements that can increase your risk of seizures. This includes EDTA, folic acid, GBL (gamma butyrolactone), GHB (gamma hydroxybutyrate), glutamine, hyssop oil, juniper, L-carnitine (levocarnitine), melatonin, rosemary, sage, wormwood, and others.

What does Ginkgo Biloba do to your body? ›

Ginkgo has a long history of use in treating blood disorders and memory issues. It is best known today as way to potentially keep your memory sharp. Laboratory studies have shown that ginkgo improves blood circulation by opening up blood vessels and making blood less sticky. It is also an antioxidant.

Does ginkgo affect blood pressure? ›

In this regard, one study found that in pre-hypertensive adults aged 21 to 57 yrs, the intake of ginkgo biloba (120 mg/day) for 3 months led to a 6% and 21% reduction in systolic and diastolic BP, respectively. In our study, ginkgo biloba had no effect on BP in elderly pre-hypertensives.

Is ginkgo bad for liver? ›

Hepatotoxicity. Despite wide spread use, ginkgo has not been specifically linked to liver injury, either in the form of transient serum enzyme elevations or clinically apparent acute liver injury. Indeed, ginkgo is sometimes used to treat acute or chronic liver injury.

Is it better to take ginkgo at night or morning? ›

Many individuals prefer taking Ginkgo Biloba in the morning, and for good reason. Starting your day with this supplement may provide an early cognitive boost. Here's why: Enhanced Alertness: Ginkgo Biloba is believed to increase blood flow to the brain, potentially improving alertness and mental clarity.

Is Ginkgo Biloba bad for your heart? ›

Ginkgo biloba is rich in antioxidants and can help reduce inflammation. It may also be beneficial for heart health, brain function, and eye health, along with several other conditions.

What does ginkgo do to the brain? ›

Ginkgo improves blood flow to the brain and acts as an antioxidant. These effects may translate into some benefits for certain medical problems, but the results have been mixed. Some studies have found that in healthy people, ginkgo might modestly boost memory and cognitive speed.

Can I take ginkgo with vitamin D? ›

Interactions between your drugs

No interactions were found between Ginkgo Biloba and Vitamin D3.

Does Ginkgo Biloba affect sleep? ›

Extracts of ginkgo biloba, or the maidenhair tree, have been used to improve concentration and memory for centuries. With relaxation-enhancing abilities, this herb can also be a suitable sleep aid to incorporate into your nightly bedtime routine, says Moskovitz.

Is 500mg of Ginkgo Biloba too much? ›

Doses over 240 mg daily aren't recommended. And ginkgo biloba isn't recommended for children. Most clinical studies used a standardized ginkgo biloba extract called EGb 761. So it's best to look for an OTC product that contains this extract for more reliable results.

What is the downside of ginkgo biloba? ›

Ginkgo biloba is specifically mentioned due to its potential to increase bleeding. Side effects of Ginkgo biloba include headache, stomach upset, and allergic skin reactions. If you're older, have a known bleeding risk, or are pregnant you should be aware that Ginkgo biloba might increase your risk of bleeding.

What drugs does ginkgo interact with? ›

It's best to avoid ginkgo biloba if you're taking warfarin, anti-seizure medications, or nifedipine. Ginkgo can also make omeprazole (Prilosec) and esomeprazole (Nexium) less effective. Other ginkgo biloba interactions include oral diabetes medications, alprazolam, and statins.

Can you take ginkgo biloba with vitamin B12? ›

Interactions between your drugs

No interactions were found between Ginkgo Biloba and Vitamin B12.

Does ginkgo interact with any medications? ›

It's best to avoid ginkgo biloba if you're taking warfarin, anti-seizure medications, or nifedipine. Ginkgo can also make omeprazole (Prilosec) and esomeprazole (Nexium) less effective. Other ginkgo biloba interactions include oral diabetes medications, alprazolam, and statins.

Are there any side effects of Ginkgo Biloba? ›

It can cause some minor side effects such as stomach upset, headache, dizziness, and allergic skin reactions. There is also some concern that ginkgo leaf extract might increase the risk of bruising and bleeding or cause arrhythmia.

Can ginkgo worsen anxiety? ›

Ginkgo may help alleviate the symptoms of anxiety. A study published in the Journal of Psychiatric Research, found that people with generalized anxiety disorder who took ginkgo experienced better anxiety relief than those who took a placebo.

Is ginkgo harmful to kidneys? ›

Ginkgo is one of 39 herbs identified by the National Kidney Foundation as harmful to patients with chronic kidney disease. "Nearly 1 in 10 adult Americans takes a dietary supplement that is potentially harmful to the kidneys, regardless of kidney disease status," said Dr.

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